ARG42315
anti-CD39 antibody [TU66] (APC)
anti-CD39 antibody [TU66] (APC) for Flow cytometry and Human
Overview
| Product Description | APC-conjugated Mouse Monoclonal antibody [TU66] recognizes CD39 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Specificity | The mouse monoclonal antibody TU66, also known as Tü66, recognizes an extracellular epitope of CD39, a 78 kDa cell surface enzyme expressed by regulatory T cells, mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | TU66 |
| Isotype | IgG2b, kappa |
| Target Name | CD39 |
| Antigen Species | Human |
| Immunogen | Human CD39. |
| Conjugation | APC |
| Alternate Names | CD39; Ecto-ATPase 1; Ecto-ATPDase 1; CD antigen CD39; NTPDase-1; ATPDase; EC 3.6.1.5; Ecto-ATP diphosphohydrolase 1; NTPDase 1; Ectonucleoside triphosphate diphosphohydrolase 1; SPG64; Ecto-apyrase; Lymphoid cell activation antigen |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified |
| Buffer | PBS and 15 mM Sodium azide. |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P49961 Human Ectonucleoside triphosphate diphosphohydrolase 1 |
|---|---|
| Gene Symbol | ENTPD1 |
| Gene Full Name | ectonucleoside triphosphate diphosphohydrolase 1 |
| Background | The protein encoded by this gene is a plasma membrane protein that hydrolyzes extracellular ATP and ADP to AMP. Inhibition of this protein's activity may confer anticancer benefits. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| Function | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. [UniProt] |
| Cellular Localization | Membrane; Multi-pass membrane protein. [UniProt] |
| Calculated MW | 58 kDa |
| PTM | The N-terminus is blocked. Palmitoylated in the N-terminal part. [UniProt] |
