ARG22912

anti-CD42a antibody [GRP-P] (PE)

anti-CD42a antibody [GRP-P] (PE) for Flow cytometry and Human,Dog

Overview

Product Description PE-conjugated Mouse Monoclonal antibody [GRP-P] recognizes CD42a
Mouse anti Human CD42a antibody, clone GRP-P recognizes the platelet GPIX glycoprotein, a 23kDa surface marker expressed by platelets and megakaryocytes. Platelet GPIX is also known as CD42a.The CD42 complex is the major platelet receptor for von Willebrand factor.
Tested Reactivity Hu, Dog
Tested Application FACS
Host Mouse
Clonality Monoclonal
Clone GRP-P
Isotype IgG1
Target Name CD42a
Antigen Species Human
Immunogen Human red blood cells and platelets.
Conjugation PE
Alternate Names Glycoprotein 9; CD antigen CD42a; CD42a; GPIX; GP-IX; Platelet glycoprotein IX

Application Instructions

Application Suggestion
Tested Application Dilution
FACSNeat - 1:5
Application Note FACS: Use 10 µl of the suggested working dilution to label 10^6 cells or 100 µl whole blood.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified by ion exchange chromatography.
Buffer PBS, 0.09% Sodium azide, 1% BSA and 5% Sucrose
Preservative 0.09% Sodium azide
Stabilizer 1% BSA and 5% Sucrose
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 2815 Human GP9

Swiss-port # P14770 Human Platelet glycoprotein IX

Gene Symbol GP9
Gene Full Name glycoprotein IX (platelet)
Background This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]
Function The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib. [UniProt]
Calculated MW 19 kDa