ARG52772
anti-CD42b antibody [SP202]
anti-CD42b antibody [SP202] for IHC-Formalin-fixed paraffin-embedded sections and Human
Cell Biology and Cellular Response antibody; Immune System antibody
Overview
| Product Description | Rabbit Monoclonal antibody [SP202] recognizes CD42b |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | SP202 |
| Isotype | IgG |
| Target Name | CD42b |
| Antigen Species | Human |
| Immunogen | Synthetic peptide from human CD42b protein. |
| Conjugation | Un-conjugated |
| Alternate Names | CD antigen CD42b; Antigen CD42b-alpha; DBPLT3; VWDP; CD42B; GP-Ib alpha; Glycoprotein Ibalpha; BDPLT1; BSS; CD42b-alpha; GPIbA; GPIb-alpha; Platelet glycoprotein Ib alpha chain; BDPLT3; GP1B |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Bone Marrow, Spleen |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by protein A/G |
| Buffer | PBS (pH 7.6), 1% BSA and < 0.1% Sodium azide |
| Preservative | < 0.1% Sodium azide |
| Stabilizer | 1% BSA |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P07359 Human Platelet glycoprotein Ib alpha chain |
|---|---|
| Background | CD42b or GPIb alpha is a surface membrane protein of platelets, megakaryocytes, and some tumor cells. It is a receptor for von Willebrand factor (VWF) and is involved in the binding of platelets to the blood vessel. CD42b is expressed by some human tumors such as megakaryoblastic leukemias and lung cancer. |
| Cellular Localization | Membrane |
| Research Area | Cell Biology and Cellular Response antibody; Immune System antibody |
| Calculated MW | 72 kDa |
| PTM | Glycocalicin, which is approximately coextensive with the extracellular part of the molecule, is cleaved off by calpain during platelet lysis. |
