ARG57529

anti-CD49a / Integrin alpha 1 antibody

anti-CD49a / Integrin alpha 1 antibody for Western blot and Human

Overview

Product Description

Goat Polyclonal antibody recognizes CD49a / Integrin alpha 1

Tested Reactivity Hu
Tested Application WB
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CD49a / Integrin alpha 1
Antigen Species Human
Immunogen Synthetic peptide around the internal region of Human CD49a / Integrin alpha 1. (C-DKHDFQDSVRIT)
Conjugation Un-conjugated
Alternate Names VLA-1; CD49a; Integrin alpha-1; Laminin and collagen receptor; VLA1; CD antigen CD49a; CD49 antigen-like family member A

Application Instructions

Application Suggestion
Tested Application Dilution
WB0.3 - 1 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Observed Size 150 kDa (glycosylated form)

Properties

Form Liquid
Purification Ammonium sulphate precipitation followed by affinity purification with immunogen.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA.
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3672 Human ITGA1

Swiss-port # P56199 Human Integrin alpha-1

Gene Symbol ITGA1
Gene Full Name integrin, alpha 1
Background This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]
Function Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth. [UniProt]
Calculated MW 131 kDa (NP_852478.1)