ARG43852
anti-CD62L / L-Selectin antibody [DREG56] (APC-Cyanine 7)
anti-CD62L / L-Selectin antibody [DREG56] (APC-Cyanine 7) for Flow cytometry and Human
Overview
| Product Description | APC-Cyanine 7-conjugated Mouse Monoclonal antibody recognizes CD62L / L-Selectin |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | DREG56 |
| Isotype | IgG1 |
| Target Name | CD62L / L-Selectin |
| Antigen Species | Human |
| Immunogen | PMA-activated Human peripheral blood leukocytes |
| Conjugation | APC-Cyanine 7 |
| Protein Full Name | L-selectin |
| Alternate Names | SELL; Selectin L; LAM-1; PLNHR; CD62L; LYAM1; LSEL; LAM1; LNHR; Leukocyte-Endothelial Cell Adhesion Molecule 1; CD62 Antigen-Like Family Member L; Leukocyte Surface Antigen Leu-8; Lymphocyte Adhesion Molecule 1; Lymph Node Homing Receptor; L-Selectin; Gp90-MEL; Lyam-1; LECAM1; HLHRc; Leu-8; TQ1; Leukocyte Adhesion Molecule 1; Pln Homing Receptor; CD62L Antigen; LEU8 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein-A affinity chromatography |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 4°C. Keep protected from prolonged exposure to light. Do not freeze. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SELL |
| Gene Full Name | Selectin L |
| Background | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. |
| Function | Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. |
| Cellular Localization | Cell membrane |
| Calculated MW | 42 kDa |
| PTM | Disulfide bond, Glycoprotein |
