ARG22049
anti-CD62L / L-Selectin antibody [MEL-14] (APC)
anti-CD62L / L-Selectin antibody [MEL-14] (APC) for Blocking,Flow cytometry,IHC-Frozen sections and Mouse
Overview
| Product Description | APC-conjugated Rat Monoclonal antibody [MEL-14] recognizes CD62L / L-Selectin |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | BL, FACS, IHC-Fr |
| Specificity | Mouse CD62L |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | MEL-14 |
| Isotype | IgG2a, kappa |
| Target Name | CD62L / L-Selectin |
| Antigen Species | Mouse |
| Immunogen | C3H/eb cloned Mouse B cell lymphoma 38C-13 |
| Conjugation | APC |
| Alternate Names | Leukocyte surface antigen Leu-8; Leukocyte adhesion molecule 1; CD antigen CD62L; PLNHR; LSEL; CD62L; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; LAM1; LNHR; TQ1; CD62 antigen-like family member L; gp90-MEL; Lymph node homing receptor; LYAM1; LECAM1; LEU8; LAM-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS, 0.1% Sodium azide and Sucrose |
| Preservative | 0.1% Sodium azide |
| Stabilizer | Sucrose |
| Concentration | 0.1 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | SELL |
| Gene Full Name | selectin, lymphocyte |
| Background | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] |
| Function | Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. [UniProt] |
| Calculated MW | 42 kDa |
