ARG20947
anti-CD72 antibody [10.1.D2]
anti-CD72 antibody [10.1.D2] for Flow cytometry,Immunoprecipitation,Cellular activation ,Blocking and Mouse
Overview
| Product Description | Mouse Monoclonal antibody [10.1.D2] recognizes CD72 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | BL, Cell-Act , FACS, IP |
| Specificity | Mouse CD72.1. The clone 10.1.D2 blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 10.1.D2 |
| Isotype | IgG2b, kappa |
| Target Name | CD72 |
| Antigen Species | Mouse |
| Immunogen | DBA/2 mouse spleen cells |
| Conjugation | Un-conjugated |
| Alternate Names | CD antigen CD72; LYB2; B-cell differentiation antigen CD72; Lyb-2; CD72b |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | BBS (pH 8.2) |
| Concentration | 0.5 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P21855 Mouse B-cell differentiation antigen CD72 |
|---|---|
| Gene Symbol | CD72 |
| Gene Full Name | CD72 antigen |
| Function | Plays a role in B-cell proliferation and differentiation. [UniProt] |
| Calculated MW | 40 kDa |
| PTM | Phosphorylated upon engagement of the B-cell receptor, probably by LYN or SYK. Phosphorylation at Tyr-7 is important for interaction with PTPN6/SHP-1 (By similarity). |
