ARG42312
anti-CD73 antibody [AD2] (APC)
anti-CD73 antibody [AD2] (APC) for Flow cytometry and Human
Overview
Product Description | APC-conjugated Mouse Monoclonal antibody [AD2] recognizes CD73 |
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Tested Reactivity | Hu |
Tested Application | FACS |
Specificity | The mouse monoclonal antibody AD2 recognizes CD73, a 70 kDa GPI-anchored 5´-nucleotidase expressed predominantly on the surface of T and B cell subsets, follicular dendritic cells and endothelial cells. |
Host | Mouse |
Clonality | Monoclonal |
Clone | AD2 |
Isotype | IgG1, kappa |
Target Name | CD73 |
Antigen Species | Human |
Immunogen | Human CD73. |
Conjugation | APC |
Alternate Names | 5'-nucleotidase; CD antigen CD73; eN; CALJA; CD73; EC 3.1.3.5; NT; Ecto-5'-nucleotidase; NT5; E5NT; 5'-NT; eNT; NTE |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified |
Buffer | PBS and 15 mM Sodium azide. |
Preservative | 15 mM Sodium azide |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | NT5E |
Gene Full Name | 5'-nucleotidase, ecto (CD73) |
Background | The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
Function | Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. [UniProt] |
Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. [UniProt] |
Calculated MW | 63 kDa |