ARG57668
anti-CD75 / ST6GAL1 antibody
anti-CD75 / ST6GAL1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse
1
Overview
Product Description | Rabbit Polyclonal antibody recognizes CD75 / ST6GAL1 |
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Tested Reactivity | Ms |
Tested Application | IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CD75 / ST6GAL1 |
Antigen Species | Human |
Immunogen | Recombinant protein of Human CD75 / ST6GAL1. |
Conjugation | Un-conjugated |
Alternate Names | SIAT1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; B-cell antigen CD75; Sialyltransferase 1; ST6Gal I; Beta-galactoside alpha-2,6-sialyltransferase 1; EC 2.4.99.1; ST6N; Alpha 2,6-ST 1; ST6GalI |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | Mouse lung |
Properties
Form | Liquid |
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Purification | Affinity purified. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q64685 Mouse Beta-galactoside alpha-2,6-sialyltransferase 1 |
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Gene Symbol | ST6GAL1 |
Gene Full Name | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
Background | This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009] |
Function | Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. [UniProt] |
Calculated MW | 47 kDa |
PTM | The soluble form derives from the membrane form by proteolytic processing. The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme. [UniProt] |