ARG66378

anti-CD80 antibody [16-10A1] (PE)

anti-CD80 antibody [16-10A1] (PE) for Flow cytometry,ICC/IF,IHC-Frozen sections and Dog,Mouse

Overview

Product Description PE-conjugated Hamster Monoclonal antibody [16-10A1] recognizes CD80
Tested Reactivity Ms, Dog
Tested Application FACS, ICC/IF, IHC-Fr
Specificity The antibody reacts with CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
Host Hamster
Clonality Monoclonal
Clone 16-10A1
Isotype IgG2
Target Name CD80
Antigen Species Mouse
Immunogen Mouse CD80-transfected CHO cell line.
Conjugation PE
Alternate Names B7.1; CTLA-4 counter-receptor B7.1; CD28LG; T-lymphocyte activation antigen CD80; B7-1; CD28LG1; B7; LAB7; Activation B7-1 antigen; CD antigen CD80; BB1

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
ICC/IFAssay-dependent
IHC-FrAssay-dependent
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified
Buffer PBS (pH 7.2), 0.09 % Sodium azide and 1 % BSA.
Preservative 0.09 % Sodium azide
Stabilizer 1 % BSA
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12519 Mouse CD80

Swiss-port # Q00609 Mouse T-lymphocyte activation antigen CD80

Gene Symbol CD80
Gene Full Name CD80 molecule
Background The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
Function Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [UniProt]
Calculated MW 33 kDa