ARG42661

anti-CD85c / LILRB5 antibody

anti-CD85c / LILRB5 antibody for Western blot and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes CD85c / LILRB5
Tested Reactivity Hu
Predict Reactivity Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CD85c / LILRB5
Antigen Species Human
Immunogen Synthetic peptide corresponding to aa. 128-173 of Human CD85c / LILRB5.
Conjugation Un-conjugated
Alternate Names LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; LIR-8; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; CD antigen CD85c; CD85C

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:500 - 1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control THP-1 and MCF7
Observed Size ~ 70 kDa

Properties

Form Liquid
Purification Affinity purification with immunogen.
Purity > 95% (by SDS-PAGE)
Buffer PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 10990 Human LILRB5

Swiss-port # O75023 Human Leukocyte immunoglobulin-like receptor subfamily B member 5

Gene Symbol LILRB5
Gene Full Name leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
Background This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function May act as receptor for class I MHC antigens. [UniProt]
Cellular Localization Membrane; Single-pass type I membrane protein. [UniProt]
Calculated MW 64 kDa