ARG42661
anti-CD85c / LILRB5 antibody
anti-CD85c / LILRB5 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CD85c / LILRB5 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CD85c / LILRB5 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide corresponding to aa. 128-173 of Human CD85c / LILRB5. |
| Conjugation | Un-conjugated |
| Alternate Names | LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; LIR-8; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; CD antigen CD85c; CD85C |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | THP-1 and MCF7 | ||||
| Observed Size | ~ 70 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O75023 Human Leukocyte immunoglobulin-like receptor subfamily B member 5 |
|---|---|
| Gene Symbol | LILRB5 |
| Gene Full Name | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 |
| Background | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | May act as receptor for class I MHC antigens. [UniProt] |
| Cellular Localization | Membrane; Single-pass type I membrane protein. [UniProt] |
| Calculated MW | 64 kDa |
