ARG57542

anti-CD94 / KLRD1 antibody [13E3]

anti-CD94 / KLRD1 antibody [13E3] for Flow cytometry,Western blot and Human

Overview

Product Description

Mouse Monoclonal antibody [13E3] recognizes CD94 / KLRD1

Tested Reactivity Hu
Tested Application FACS, WB
Host Mouse
Clonality Monoclonal
Clone 13E3
Isotype IgG1, kappa
Target Name CD94 / KLRD1
Antigen Species Human
Immunogen Recombinant Human CD94 / KLRD1 (aa. 32-179) purified from E. coli
Conjugation Un-conjugated
Alternate Names KP43; CD antigen CD94; CD94; Natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor

Application Instructions

Application Suggestion
Tested Application Dilution
FACS2 - 5 µg/10^6 cells
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein A.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3824 Human KLRD1

Swiss-port # Q13241 Human Natural killer cells antigen CD94

Gene Symbol KLRD1
Gene Full Name killer cell lectin-like receptor subfamily D, member 1
Background Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt]
Calculated MW 21 kDa