ARG22078
anti-CD94 / KLRD1 antibody [18d3] (FITC)
anti-CD94 / KLRD1 antibody [18d3] (FITC) for Flow cytometry and Mouse
Overview
| Product Description | FITC-conjugated Rat Monoclonal antibody [18d3] recognizes CD94 / KLRD1 |
|---|---|
| Tested Reactivity | Ms |
| Tested Application | FACS |
| Specificity | Mouse CD94 |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 18d3 |
| Isotype | IgG2a, kappa |
| Target Name | CD94 / KLRD1 |
| Antigen Species | Mouse |
| Immunogen | CHO cells transfected with the B6 allele of CD94 |
| Conjugation | FITC |
| Alternate Names | KP43; CD antigen CD94; CD94; Natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS and 0.1% Sodium azide. |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.5 mg/ml |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | KLRD1 |
| Gene Full Name | killer cell lectin-like receptor, subfamily D, member 1 |
| Background | Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt] |
| Calculated MW | 21 kDa |
