ARG42271

anti-CD94 / KLRD1 antibody [HP-3D9] (FITC)

anti-CD94 / KLRD1 antibody [HP-3D9] (FITC) for Flow cytometry and Human

Overview

Product Description FITC-conjugated Mouse Monoclonal antibody [HP-3D9] recognizes CD94 / KLRD1
Tested Reactivity Hu
Tested Application FACS
Specificity The mouse monoclonal antibody HP-3D9 recognizes an extracellular epitope of CD94, a 70 kDa type II transmembrane glycoprotein expressed on NK cells, NK-T cells, and subsets of CD8+ T cells and gamma/delta T cells.
Host Mouse
Clonality Monoclonal
Clone HP-3D9
Isotype IgG1, kappa
Target Name CD94 / KLRD1
Antigen Species Human
Immunogen Cultured Human NK cells.
Conjugation FITC
Alternate Names KP43; CD antigen CD94; CD94; Natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; NK cell receptor

Application Instructions

Application Suggestion
Tested Application Dilution
FACS4 µl / 100 µl of whole blood or 10^6 cells
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified
Buffer PBS and 15 mM Sodium azide.
Preservative 15 mM Sodium azide
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 3824 Human KLRD1

Swiss-port # Q13241 Human Natural killer cells antigen CD94

Gene Symbol KLRD1
Gene Full Name killer cell lectin-like receptor subfamily D, member 1
Background Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
Function Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. [UniProt]
Cellular Localization Membrane; Single-pass type II membrane protein. [UniProt]
Calculated MW 21 kDa