ARG10880
anti-CDC6 antibody [cdc6 9H8/5]
anti-CDC6 antibody [cdc6 9H8/5] for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and S. cerevisiae
Overview
| Product Description | Mouse Monoclonal antibody [cdc6 9H8/5] recognizes CDC6 |
|---|---|
| Tested Reactivity | S. cerevisiae |
| Tested Application | IHC-P, IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | cdc6 9H8/5 |
| Isotype | IgG1 |
| Target Name | CDC6 |
| Antigen Species | Yeast |
| Immunogen | cdc6 from S. Cerevisiae. |
| Conjugation | Un-conjugated |
| Alternate Names | p62; HsCDC18; CDC18L; Cdc18-related protein; Cell division control protein 6 homolog; CDC6-related protein; HsCdc18; cdc6; HsCDC6 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified by affinity chromatography. |
| Buffer | PBS and 0.02% Sodium azide. |
| Preservative | 0.02% Sodium azide |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Gene Symbol | CDC6 |
|---|---|
| Gene Full Name | cell division cycle 6 |
| Background | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008] |
| Function | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. [UniProt] |
| Calculated MW | 63 kDa |
