ARG41364
anti-CDC7 antibody
anti-CDC7 antibody for Flow cytometry,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CDC7 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CDC7 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide derived from Human CDC7. |
| Conjugation | Un-conjugated |
| Alternate Names | CDC7L1; huCDC7; CDC7-related kinase; huCdc7; Hsk1; Cell division cycle 7-related protein kinase; HsCdc7; EC 2.7.11.1; HsCDC7 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Observed Size | ~ 65 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O00311 Human Cell division cycle 7-related protein kinase Swiss-port # Q9Z0H0 Mouse Cell division cycle 7-related protein kinase |
|---|---|
| Gene Symbol | CDC7 |
| Gene Full Name | cell division cycle 7 |
| Background | This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008] |
| Function | Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 64 kDa |
