ARG57340

anti-CHD2 antibody

Ordering Information

Package

Price (USD)

100 μl

359.00

50 μl

249.00

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Overview

Product Description	Rabbit Polyclonal antibody recognizes CHD2
Tested Reactivity	Hu
Tested Application	ICC/IF, WB
Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Target Name	CHD2
Antigen Species	Human
Immunogen	Recombinant Protein of Human CHD2.
Conjugation	Un-conjugated
Alternate Names	ATP-dependent helicase CHD2; EC 3.6.4.12; EEOC; Chromodomain-helicase-DNA-binding protein 2; CHD-2

Application Instructions

Application Suggestion

Tested Application	Dilution
ICC/IF	1:10 - 1:100
WB	1:500 - 1:2000

Application Note

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Positive Control

HeLa

Properties

Form	Liquid
Purification	Affinity purification with immunogen.
Buffer	PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative	0.02% Sodium azide
Stabilizer	50% Glycerol
Storage Instruction	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note	For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links	GeneID: 1106 Human CHD2 Swiss-port # O14647 Human Chromodomain-helicase-DNA-binding protein 2
Gene Symbol	CHD2
Gene Full Name	chromodomain helicase DNA binding protein 2
Background	The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function	DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression (By similarity). [UniProt]
Calculated MW	211 kDa