ARG40134
anti-CHRAC17 antibody
anti-CHRAC17 antibody for Western blot,Flow cytometry and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CHRAC17 |
|---|---|
| Tested Reactivity | Hu |
| Predict Reactivity | Ms, Rat, Bov |
| Tested Application | FACS, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CHRAC17 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 5-34 of Human CHRAC17. |
| Conjugation | Un-conjugated |
| Alternate Names | DNA polymerase II subunit 3; CHRAC-17; HuCHRAC17; Chromatin accessibility complex 17 kDa protein; YBL1; AsTP; DNA polymerase epsilon subunit p17; Arsenic-transactivated protein; p17; CHARAC17; CHRAC17; EC 2.7.7.7; DNA polymerase epsilon subunit 3 |
Application Instructions
| Application Suggestion |
|
||||||
|---|---|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | K562 |
Properties
| Form | Liquid |
|---|---|
| Purification | Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Buffer | PBS and 0.09% (W/V) Sodium azide. |
| Preservative | 0.09% (W/V) Sodium azide. |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | POLE3 |
| Gene Full Name | polymerase (DNA directed), epsilon 3, accessory subunit |
| Background | POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004] |
| Function | Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 17 kDa |
