ARG40134

anti-CHRAC17 antibody

anti-CHRAC17 antibody for Western blot,Flow cytometry and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes CHRAC17
Tested Reactivity Hu
Predict Reactivity Ms, Rat, Bov
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CHRAC17
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 5-34 of Human CHRAC17.
Conjugation Un-conjugated
Alternate Names DNA polymerase II subunit 3; CHRAC-17; HuCHRAC17; Chromatin accessibility complex 17 kDa protein; YBL1; AsTP; DNA polymerase epsilon subunit p17; Arsenic-transactivated protein; p17; CHARAC17; CHRAC17; EC 2.7.7.7; DNA polymerase epsilon subunit 3

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:10 - 1:50
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control K562

Properties

Form Liquid
Purification Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 54107 Human POLE3

Swiss-port # Q9NRF9 Human DNA polymerase epsilon subunit 3

Gene Symbol POLE3
Gene Full Name polymerase (DNA directed), epsilon 3, accessory subunit
Background POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM, Apr 2004]
Function Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1. [UniProt]
Cellular Localization Nucleus. [UniProt]
Calculated MW 17 kDa