ARG58425

anti-CHRNE antibody

anti-CHRNE antibody for Flow cytometry,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CHRNE
Tested Reactivity Hu, Ms, Rat
Tested Application FACS, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CHRNE
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 409-443 of Human CHRNE.
Conjugation Un-conjugated
Alternate Names FCCMS; CMS1E; CMS1D; SCCMS; CMS2A; Acetylcholine receptor subunit epsilon; CMS4B; CMS4C; ACHRE; CMS4A

Application Instructions

Application Suggestion
Tested Application Dilution
FACS1:25
WB1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human skeletal muscle

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 11448 Mouse CHRNE

GeneID: 1145 Human CHRNE

GeneID: 29422 Rat CHRNE

Gene Symbol CHRNE
Gene Full Name cholinergic receptor, nicotinic, epsilon (muscle)
Background Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009]
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [UniProt]
Calculated MW 55 kDa