ARG41183

anti-CIAO1 antibody

anti-CIAO1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CIAO1
Tested Reactivity Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CIAO1
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 1-339 of Human CIAO1 (NP_004795.1).
Conjugation Un-conjugated
Alternate Names Probable cytosolic iron-sulfur protein assembly protein CIAO1; WDR39; WD repeat-containing protein 39; CIA1

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:200
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse heart
Observed Size 38 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 26371 Mouse CIAO1

GeneID: 29231 Rat CIAO1

Swiss-port # Q5M7T1 Rat Probable cytosolic iron-sulfur protein assembly protein CIAO1

Swiss-port # Q99KN2 Mouse Probable cytosolic iron-sulfur protein assembly protein CIAO1

Gene Symbol CIAO1
Gene Full Name cytosolic iron-sulfur assembly component 1
Function Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. [UniProt]
Calculated MW 38 kDa