ARG44640
anti-CINP antibody
anti-CINP antibody for Immunoprecipitation,Western blot and Human
Overview
| Product Description | Mouse Monoclonal antibody recognizes CINP |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IP, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a |
| Target Name | CINP |
| Antigen Species | Human |
| Conjugation | Un-conjugated |
| Alternate Names | CINP; Cyclin Dependent Kinase 2 Interacting Protein; Cyclin-Dependent Kinase 2-Interacting Protein; CDK2-Interacting Protein; MGC849 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A purification |
| Buffer | PBS with 0.09% sodium azide |
| Preservative | 0.09% sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q9BW66 Human Cyclin-dependent kinase 2-interacting protein |
|---|---|
| Gene Symbol | CINP |
| Gene Full Name | Cyclin Dependent Kinase 2 Interacting Protein |
| Background | The protein encoded by this gene is reported to be a component of the DNA replication complex as well as a genome-maintenance protein. It may interact with proteins important for replication initiation and has been shown to bind chromatin at the G1 phase of the cell cycle and dissociate from chromatin with replication initiation. It may also serve to regulate checkpoint signaling as part of the DNA damage response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] |
| Function | As part of 55LCC complex, also involved in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles. [UniProt] |
| Cellular Localization | Nucleus. [UniProt] |
| Calculated MW | 24 kDa |
| PTM | Acetylation, Phosphoprotein. [UniProt] |
