ARG65671

anti-CK1 epsilon antibody

anti-CK1 epsilon antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human

Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes CK1 epsilon
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CK1 epsilon
Antigen Species Human
Immunogen Fusion protein around the C-terminus of Human CK1 epsilon.
Conjugation Un-conjugated
Alternate Names tau; CK1epsilon; Casein kinase I isoform epsilon; AI426939; CKIe; CKI-epsilon; AW457082; AI551861; EC 2.7.11.1; KC1epsilon

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay-dependent
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control IHC: Human cervical cancer.
WB: Hela and A431 cell.

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.05% Sodium azide and 50% Glycerol
Preservative 0.05% Sodium azide
Stabilizer 50% Glycerol
Concentration 3.1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1454 Human CSNK1E

Swiss-port # P49674 Human Casein kinase I isoform epsilon

Gene Symbol CSNK1E
Gene Full Name casein kinase 1, epsilon
Background This locus represents naturally occurring readthrough transcription between the neighboring LOC400927 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene) and CSNK1E (casein kinase I isoform epsilon) genes on chromosome 22. The readthrough transcript encodes the same protein as the downstream gene product (casein kinase I isoform epsilon). [provided by RefSeq, Feb 2014]
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation. [UniProt]
Research Area Signaling Transduction antibody
Calculated MW 47 kDa