ARG64566

anti-CLEC2 / CLEC1B antibody

anti-CLEC2 / CLEC1B antibody for Western blot and Human

Immune System antibody

Overview

Product Description Goat Polyclonal antibody recognizes CLEC2 / CLEC1B
Tested Reactivity Hu
Tested Application WB
Specificity This antibody is expected to recognize both reported isoforms (NP_001092901.1; NP_057593.3)
Host Goat
Clonality Polyclonal
Isotype IgG
Target Name CLEC2 / CLEC1B
Antigen Species Human
Immunogen KGHKCSPCDTNWRY
Conjugation Un-conjugated
Alternate Names CLEC2; C-type lectin domain family 1 member B; CLEC2B; PRO1384; C-type lectin-like receptor 2; CLEC-2; 1810061I13Rik; QDED721

Application Instructions

Application Suggestion
Tested Application Dilution
WB1 - 3 µg/ml
Application Note WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
Preservative 0.02% Sodium azide
Stabilizer 0.5% BSA
Concentration 0.5 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 51266 Human CLEC1B

Swiss-port # Q9P126 Human C-type lectin domain family 1 member B

Background Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
Research Area Immune System antibody
Calculated MW 27 kDa
PTM Glycosylated.
Phosphorylated on tyrosine residue in response to rhodocytin binding.