ARG44596
anti-CLEC4C / BDCA2 antibody [15E3] (APC)
anti-CLEC4C / BDCA2 antibody [15E3] (APC) for Flow cytometry and Human
Overview
| Product Description | APC-conjugated Mouse Monoclonal antibody recognizes CLEC4C / BDCA2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | FACS |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 15E3 |
| Isotype | IgG1 kappa |
| Target Name | CLEC4C / BDCA2 |
| Antigen Species | Human |
| Conjugation | APC |
| Alternate Names | CLEC4C; C-Type Lectin Domain Family 4 Member C; BDCA2; HECL; DLEC; CLECSF11; CLECSF7; CD303; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 7; C-Type Lectin Superfamily Member 7; Dendritic Lectin; BDCA-2; C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 11; C-Type Lectin Domain Family 4, Member C; Blood Dendritic Cell Antigen 2 Protein; Blood Dendritic Cell Antigen 2; Dendritic Cell Lectin B; CD303 Antigen; PRO34150 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
| Form | Liquid |
|---|---|
| Purification | Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Buffer | PBS (pH 7.4) and 15 mM Sodium azide |
| Preservative | 15 mM Sodium azide |
| Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # Q8WTT0 Human C-type lectin domain family 4 member C |
|---|---|
| Gene Symbol | CLEC4C |
| Gene Full Name | C-Type Lectin Domain Family 4 Member C |
| Background | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| Function | May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. [UniProt] |
| Cellular Localization | Cell membrane, Membrane. [UniProt] |
| Calculated MW | 25 kDa |
| PTM | Disulfide bond, Glycoprotein. [UniProt] |
