ARG41949
anti-CLIP2 / CLIP115 antibody
anti-CLIP2 / CLIP115 antibody for Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CLIP2 / CLIP115 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CLIP2 / CLIP115 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human CLIP2. |
| Conjugation | Un-conjugated |
| Alternate Names | WSCR4; WSCR3; CLIP; Cytoplasmic linker protein 2; Williams-Beuren syndrome chromosomal region 3 protein; WBSCR4; CAP-Gly domain-containing linker protein 2; Cytoplasmic linker protein 115; WBSCR3; Williams-Beuren syndrome chromosomal region 4 protein; CYLN2; CLIP-115 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Observed Size | 120 ~ 130 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purification with immunogen. |
| Purity | > 95% (by SDS-PAGE) |
| Buffer | PBS (pH 7.2), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Concentration | 1 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CLIP2 |
| Gene Full Name | CAP-GLY domain containing linker protein 2 |
| Background | The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] |
| Function | Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocations (By similarity). [UniProt] |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton. Note=Localizes preferentially to the ends of tyrosinated microtubules. [UniProt] |
| Calculated MW | 116 kDa |
