ARG55215
anti-CNOT4 antibody
anti-CNOT4 antibody for Western blot and Human,Mouse
Cell Biology and Cellular Response antibody; Gene Regulation antibody
Overview
| Product Description | Mouse Monoclonal antibody recognizes CNOT4 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 343CT14.6.5 |
| Isotype | IgG2a, kappa |
| Target Name | CNOT4 |
| Antigen Species | Human |
| Immunogen | Recombinant protein of Human CNOT4 (Swiss: O95628). |
| Conjugation | Un-conjugated |
| Alternate Names | CLONE243; NOT4; NOT4H; EC 6.3.2.-; CCR4-associated factor 4; Potential transcriptional repressor NOT4Hp; CCR4-NOT transcription complex subunit 4; E3 ubiquitin-protein ligase CNOT4 |
Application Instructions
| Application Suggestion |
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|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse heart |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein G. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # O95628 Human CCR4-NOT transcription complex subunit 4 Swiss-port # Q8BT14 Mouse CCR4-NOT transcription complex subunit 4 |
|---|---|
| Gene Symbol | CNOT4 |
| Gene Full Name | CCR4-NOT transcription complex, subunit 4 |
| Background | The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010] |
| Function | Has E3 ubiquitin ligase activity. Involved in activation of the JAK/STAT pathway. [UniProt] |
| Cellular Localization | Cytoplasm. Nucleus |
| Research Area | Cell Biology and Cellular Response antibody; Gene Regulation antibody |
| Calculated MW | 64 kDa |
| PTM | Autoubiquitinated. |
