ARG42080
anti-CNTN2 / Contactin 2 antibody
anti-CNTN2 / Contactin 2 antibody for Western blot,ICC/IF,Flow cytometry and Human,Mouse
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CNTN2 / Contactin 2 |
|---|---|
| Tested Reactivity | Hu, Ms |
| Tested Application | FACS, ICC/IF, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CNTN2 / Contactin 2 |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human CNTN2 / Contactin 2. |
| Conjugation | Un-conjugated |
| Alternate Names | TAG-1; AXT; TAX; Contactin-2; TAX-1; TAX1; FAME5; Transient axonal glycoprotein 1; Axonin-1; Axonal glycoprotein TAG-1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | U87-MG | ||||||||
| Observed Size | ~ 140 kDa | ||||||||
| Assay Time | Q02246 |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CNTN2 |
| Gene Full Name | contactin 2 (axonal) |
| Background | This gene encodes a member of the contactin family of proteins, part of the immunoglobulin superfamily of cell adhesion molecules. The encoded glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein plays a role in the proliferation, migration, and axon guidance of neurons of the developing cerebellum. A mutation in this gene may be associated with adult myoclonic epilepsy. [provided by RefSeq, Sep 2016] |
| Function | In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion. [UniProt] |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons. [UniProt] |
| Calculated MW | 113 kDa |
