ARG43335
anti-CNTNAP4 / Caspr 4 antibody
anti-CNTNAP4 / Caspr 4 antibody for Western blot and Human,Mouse
Overview
Product Description | Rabbit Polyclonal antibody recognizes CNTNAP4 / Caspr 4 |
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Tested Reactivity | Hu, Ms |
Tested Application | WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CNTNAP4 / Caspr 4 |
Antigen Species | Human |
Immunogen | Synthetic peptide derived from Human CNTNAP4 / Caspr 4. |
Conjugation | Un-conjugated |
Alternate Names | CASPR4; Cell recognition molecule Caspr4; Contactin-associated protein-like 4 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
Positive Control | LoVo | ||||
Observed Size | ~ 145 kDa |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # Q99P47 Mouse Contactin-associated protein-like 4 Swiss-port # Q9C0A0 Human Contactin-associated protein-like 4 |
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Gene Symbol | CNTNAP4 |
Gene Full Name | contactin associated protein-like 4 |
Background | This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016] |
Function | Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system (By similarity). [UniProt] |
Cellular Localization | Cell junction, synapse, presynaptic cell membrane; Single-pass type I membrane protein. Note=Specifically present within the presynaptic compartment of synapses. [UniProt] |
Calculated MW | 145 kDa |