ARG54963

anti-COX6A2 antibody

anti-COX6A2 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human

Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes COX6A2
Tested Reactivity Hu
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name COX6A2
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 37-66 (Center) of Human COX6A2.
Conjugation Un-conjugated
Alternate Names COX6AH; Cytochrome c oxidase subunit VIA-muscle; Cytochrome c oxidase polypeptide VIa-heart; Cytochrome c oxidase subunit 6A2, mitochondrial; COX VIa-M; COXVIAH

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay-dependent
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human skeletal muscle

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1339 Human COX6A2

Swiss-port # Q02221 Human Cytochrome c oxidase subunit 6A2, mitochondrial

Gene Symbol COX6A2
Gene Full Name cytochrome c oxidase subunit VIa polypeptide 2
Background Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq, Jul 2008]
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. [UniProt]
Cellular Localization Mitochondrion inner membrane.
Research Area Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 11 kDa