ARG54964

anti-COX6B1 antibody

anti-COX6B1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human

Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes COX6B1
Tested Reactivity Hu
Predict Reactivity Mk
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name COX6B1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 59-86 (C-terminus) of Human COX6B1.
Conjugation Un-conjugated
Alternate Names COXVIb1; Cytochrome c oxidase subunit 6B1; Cytochrome c oxidase subunit VIb isoform 1; COXG; COX VIb-1; COX6B

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-PAssay-dependent
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control A549

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1340 Human COX6B1

Swiss-port # P14854 Human Cytochrome c oxidase subunit 6B1

Gene Symbol COX6B1
Gene Full Name cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
Background Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq, Jan 2010]
Function Connects the two COX monomers into the physiological dimeric form. [UniProt]
Cellular Localization Mitochondrion intermembrane space
Research Area Cancer antibody; Controls and Markers antibody; Metabolism antibody; Signaling Transduction antibody
Calculated MW 10 kDa