ARG58401
anti-COX7A2 antibody
anti-COX7A2 antibody for Western blot and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes COX7A2 |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | COX7A2 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 33-115 of Human COX7A2 (NP_001856.2). |
| Conjugation | Un-conjugated |
| Alternate Names | VIIAL; COX7AL; COXVIIa-L; COXVIIAL; Cytochrome c oxidase subunit VIIa-L; Cytochrome c oxidase subunit 7A2, mitochondrial; COX7AL1; Cytochrome c oxidase subunit VIIa-liver/heart; Cytochrome c oxidase subunit VIIaL |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | HeLa | ||||
| Observed Size | 11 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P14406 Human Cytochrome c oxidase subunit 7A2, mitochondrial |
|---|---|
| Gene Symbol | COX7A2 |
| Gene Full Name | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) |
| Background | Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009] |
| Function | This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. [UniProt] |
| Cellular Localization | Mitochondrion inner membrane. [UniProt] |
| Calculated MW | 9 kDa |
