ARG65705
anti-CRABP2 antibody
anti-CRABP2 antibody for Western blot,ICC/IF and Human,Mouse
Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes CRABP2 |
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Tested Reactivity | Hu, Ms |
Predict Reactivity | Rat |
Tested Application | ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CRABP2 |
Antigen Species | Human |
Immunogen | Recombinant protein of Human CRABP2 |
Conjugation | Un-conjugated |
Alternate Names | Cellular retinoic acid-binding protein II; CRABP-II; RBP6; Cellular retinoic acid-binding protein 2 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | SW480 |
Properties
Form | Liquid |
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Purification | Affinity purification with immunogen. |
Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
Preservative | 0.02% Sodium azide |
Stabilizer | 50% Glycerol |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links |
Swiss-port # P22935 Mouse Cellular retinoic acid-binding protein 2 Swiss-port # P29373 Human Cellular retinoic acid-binding protein 2 |
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Gene Symbol | CRABP2 |
Gene Full Name | cellular retinoic acid binding protein 2 |
Background | This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010] |
Function | Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. [UniProt] |
Research Area | Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody |
Calculated MW | 16 kDa |
PTM | Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. |