ARG65705

anti-CRABP2 antibody

anti-CRABP2 antibody for Western blot,ICC/IF and Human,Mouse

Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes CRABP2
Tested Reactivity Hu, Ms
Predict Reactivity Rat
Tested Application ICC/IF, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CRABP2
Antigen Species Human
Immunogen Recombinant protein of Human CRABP2
Conjugation Un-conjugated
Alternate Names Cellular retinoic acid-binding protein II; CRABP-II; RBP6; Cellular retinoic acid-binding protein 2

Application Instructions

Application Suggestion
Tested Application Dilution
ICC/IF1:20 - 1:100
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control SW480

Properties

Form Liquid
Purification Affinity purification with immunogen.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12904 Mouse CRABP2

GeneID: 1382 Human CRABP2

Swiss-port # P22935 Mouse Cellular retinoic acid-binding protein 2

Swiss-port # P29373 Human Cellular retinoic acid-binding protein 2

Gene Symbol CRABP2
Gene Full Name cellular retinoic acid binding protein 2
Background This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010]
Function Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. [UniProt]
Research Area Cancer antibody; Gene Regulation antibody; Signaling Transduction antibody
Calculated MW 16 kDa
PTM Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation.