ARG59582

anti-CRHBP antibody

anti-CRHBP antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes CRHBP
Tested Reactivity Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CRHBP
Antigen Species Human
Immunogen Recombinant fusion protein corresponding to aa. 25-322 of Human CRHBP (NP_001873.2).
Conjugation Un-conjugated
Alternate Names CRFBP; CRH-BP; CRF-binding protein; Corticotropin-releasing hormone-binding protein; Corticotropin-releasing factor-binding protein; CRF-BP

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
WB1:500 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Rat brain
Observed Size 37 kDa

Properties

Form Liquid
Purification Affinity purified.
Buffer PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 50% Glycerol
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Gene Symbol CRHBP
Gene Full Name corticotropin releasing hormone binding protein
Background Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008]
Function Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. [UniProt]
Cellular Localization Secreted. [UniProt]
Calculated MW 36 kDa