ARG42071

anti-CRLS1 antibody

anti-CRLS1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human

Overview

Product Description Rabbit Polyclonal antibody recognizes CRLS1
Tested Reactivity Hu
Predict Reactivity Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CRLS1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide between aa. 198-226 of Human CRLS1.
Conjugation Un-conjugated
Alternate Names CLS; CLS1; GCD10; C20orf155; dJ967N21.6; Cardiolipin synthase (CMP-forming); CLS; EC 2.7.8.41; Protein GCD10 homolog

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control T47D
Observed Size ~ 32 kDa

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 54675 Human CRLS1

Swiss-port # Q9UJA2 Human Cardiolipin synthase (CMP-forming)

Gene Symbol CRLS1
Gene Full Name cardiolipin synthase 1
Background This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function. [provided by RefSeq, Apr 2016]
Function Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. [UniProt]
Cellular Localization Mitochondrion inner membrane; Multi-pass membrane protein. [UniProt]
Calculated MW 33 kDa