ARG56794

anti-CXCL11 / I-TAC antibody (Biotin)

anti-CXCL11 / I-TAC antibody (Biotin) for ELISA,Western blot and Mouse,Human

Overview

Product Description Biotin-conjugated Rabbit Polyclonal antibody recognizes CXCL11 / I-TAC
Tested Reactivity Hu, Ms
Tested Application ELISA, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name CXCL11 / I-TAC
Antigen Species Human
Immunogen E.coli derived Recombinant Human I-TAC (CXCL11).
(FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF)
Conjugation Biotin
Alternate Names SCYB9B; SCYB11; C-X-C motif chemokine 11; Beta-R1; b-R1; Interferon gamma-inducible protein 9; I-TAC; Small-inducible cytokine B11; Interferon-inducible T-cell alpha chemoattractant; H174; IP-9; IP9

Application Instructions

Application Suggestion
Tested Application Dilution
ELISADirect: 0.25 - 1.0 µg/ml
Sandwich: 0.25 - 1.0 µg/ml with ARG56685 as a capture antibody
WB0.1 - 0.2 µg/ml
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified by affinity chromatography.
Buffer PBS (pH 7.2)
Concentration 1 mg/ml
Storage Instruction Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 56066 Mouse CXCL11

GeneID: 6373 Human CXCL11

Swiss-port # O14625 Human C-X-C motif chemokine 11

Swiss-port # Q9JHH5 Mouse C-X-C motif chemokine 11

Gene Symbol CXCL11
Gene Full Name chemokine (C-X-C motif) ligand 11
Background Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Function Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. [UniProt]
Highlight Related products:
CXCL11 antibodies; CXCL11 ELISA Kits; Anti-Rabbit IgG secondary antibodies;
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Calculated MW 10 kDa