ARG66056
anti-CXCL13 / BCA1 antibody (Biotin)
anti-CXCL13 / BCA1 antibody (Biotin) for ELISA,Western blot and Human
Overview
Product Description | Biotin-conjugated Rabbit Polyclonal antibody recognizes CXCL13 / BCA1 |
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Tested Reactivity | Hu |
Tested Application | ELISA, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CXCL13 / BCA1 |
Antigen Species | Human |
Immunogen | E. coli derived recombinant Human CXCL13 / BCA1. (VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP) |
Conjugation | Biotin |
Alternate Names | BCA-1; Angie; C-X-C motif chemokine 13; CXC chemokine BLC; ANGIE2; B lymphocyte chemoattractant; B cell-attracting chemokine 1; BLR1L; Small-inducible cytokine B13; SCYB13; ANGIE; BLC; BCA1 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified by affinity chromatography. |
Buffer | PBS (pH 7.2) |
Concentration | 1 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CXCL13 |
Gene Full Name | chemokine (C-X-C motif) ligand 13 |
Background | B lymphocyte chemoattractant, independently cloned and named Angie, is an antimicrobial peptide and CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Oct 2014] |
Function | Chemotactic for B-lymphocytes but not for T-lymphocytes, monocytes and neutrophils. Does not induce calcium release in B-lymphocytes. Binds to BLR1/CXCR5. [UniProt] |
Calculated MW | 13 kDa |