ARG66105
anti-CXCL14 antibody (Biotin)
anti-CXCL14 antibody (Biotin) for ELISA,Western blot and Human
Overview
Product Description | Biotin-conjugated Rabbit Polyclonal antibody recognizes CXCL14 |
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Tested Reactivity | Hu |
Tested Application | ELISA, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | CXCL14 |
Antigen Species | Human |
Immunogen | E. coli derived recombinant Human CXCL14. (SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE) |
Conjugation | Biotin |
Alternate Names | MIP-2G; KS1; BMAC; Small-inducible cytokine B14; KEC; C-X-C motif chemokine 14; MIP-2g; Chemokine BRAK; MIP2G; BRAK; NJAC; SCYB14 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified by affinity chromatography. |
Buffer | PBS (pH 7.2) |
Concentration | 1 mg/ml |
Storage Instruction | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CXCL14 |
Gene Full Name | chemokine (C-X-C motif) ligand 14 |
Background | This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq, Sep 2014] |
Function | Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays. [UniProt] |
Calculated MW | 13 kDa |
PTM | Ubiquitinated, followed by degradation by the proteasome. |