ARG59925
anti-CXXC1 antibody
anti-CXXC1 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections,ICC/IF and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes CXXC1 |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | CXXC1 |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 1-210 of Human CXXC1 (NP_001095124.1). |
| Conjugation | Un-conjugated |
| Alternate Names | 5830420C16Rik; CFP1; HsT2645; PHF18; 2410002I16Rik; CGBP; ZCGPC1; SPP1; hCGBP; PCCX1; CXXC-type zinc finger protein 1; CpG-binding protein; PHD finger and CXXC domain-containing protein 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| Positive Control | Rat testis and HepG2 | ||||||||
| Observed Size | 75 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CXXC1 |
| Gene Full Name | CXXC finger protein 1 |
| Background | This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development. [provided by RefSeq, Sep 2015] |
| Function | Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG. [UniProt] |
| Cellular Localization | Nucleus speckle. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes. [UniProt] |
| Calculated MW | 76 kDa |
| PTM | May be regulated by proteolysis. [UniProt] |
