ARG55081
anti-Cadherin 8 antibody
anti-Cadherin 8 antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Neuroscience antibody; Signaling Transduction antibody
Overview
Product Description | Rabbit Polyclonal antibody recognizes Cadherin 8 |
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Tested Reactivity | Hu |
Tested Application | IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | Cadherin 8 |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 33-63 (N-terminus) of Human Cadherin 8. |
Conjugation | Un-conjugated |
Alternate Names | Cadherin-8; Nbla04261 |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
Positive Control | SH-SY5Y |
Properties
Form | Liquid |
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Purification | Purification with Protein A and immunogen peptide. |
Buffer | PBS and 0.09% (W/V) Sodium azide |
Preservative | 0.09% (W/V) Sodium azide |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CDH8 |
Gene Full Name | cadherin 8, type 2 |
Background | This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008] |
Function | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. [UniProt] |
Cellular Localization | Cell membrane; Single-pass type I membrane protein |
Research Area | Neuroscience antibody; Signaling Transduction antibody |
Calculated MW | 88 kDa |