ARG41001
anti-Calcineurin B antibody
anti-Calcineurin B antibody for ICC/IF,Western blot and Human,Mouse,Rat
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Calcineurin B |
|---|---|
| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | ICC/IF, WB |
| Specificity | This antibody might reacts to both PPP3R1 (100%) and PPP3R2 (84%) protein based on sequence analysis. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Calcineurin B |
| Antigen Species | Human |
| Immunogen | Recombinant fusion protein corresponding to aa. 11-170 of Human Calcineurin B (NP_000936.1). |
| Conjugation | Un-conjugated |
| Alternate Names | CALNB1; Calcineurin subunit B type 1; CNB1; Protein phosphatase 3 regulatory subunit B alpha isoform 1; CNB; Protein phosphatase 2B regulatory subunit 1 |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | HL-60 | ||||||
| Observed Size | 15 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | PPP3R1 |
| Gene Full Name | protein phosphatase 3, regulatory subunit B, alpha |
| Function | Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. [UniProt] |
| Cellular Localization | Cytoplasm, cytosol. Cell membrane. Cell membrane, sarcolemma. Membrane; Lipid-anchor. Note=Translocates from the cytosol to the sarcolemma in a CIB1-dependent manner during cardiomyocytes hypertrophy. [UniProt] |
| Calculated MW | 19 kDa |
