ARG56226
anti-Calcitonin Receptor antibody
anti-Calcitonin Receptor antibody for Flow cytometry,ICC/IF,Western blot and Human
Overview
Product Description | Rabbit Polyclonal antibody recognizes Calcitonin Receptor |
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Tested Reactivity | Hu |
Tested Application | FACS, ICC/IF, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | Calcitonin Receptor |
Antigen Species | Human |
Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 445-474 (C-terminus) of Human Calcitonin Receptor. |
Conjugation | Un-conjugated |
Alternate Names | CT-R; CTR1; CTR; CRT; Calcitonin receptor |
Application Instructions
Application Suggestion |
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Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
Positive Control | MCF7 |
Properties
Form | Liquid |
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Purification | Purification with Protein A and immunogen peptide. |
Buffer | PBS and 0.09% (W/V) Sodium azide. |
Preservative | 0.09% (W/V) Sodium azide. |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CALCR |
Gene Full Name | calcitonin receptor |
Background | This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009] |
Function | This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. [UniProt] |
Cellular Localization | Cell membrane; Multi-pass membrane protein. |
Calculated MW | 55 kDa |