ARG62377
anti-Calcitonin antibody [CT10]
anti-Calcitonin antibody [CT10] for IHC-Formalin-fixed paraffin-embedded sections,IHC-Frozen sections and Human
Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody [CT10] recognizes Calcitonin |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-Fr, IHC-P |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CT10 |
| Isotype | IgG1 |
| Target Name | Calcitonin |
| Antigen Species | Human |
| Immunogen | Synthetic calcitonin. |
| Conjugation | Un-conjugated |
| Alternate Names | CALC1; Calcitonin carboxyl-terminal peptide; CCP; PDN-21; CT |
Application Instructions
| Application Note | IHC-Fr and IHC-P: 1: 40-1: 80. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|---|
| Positive Control | Human Thyroid and Medullary Carcinoma of Thyroid tissues |
Properties
| Form | Liquid |
|---|---|
| Buffer | PBS (pH 7.5) and 0.1% Sodium azide |
| Preservative | 0.1% Sodium azide |
| Concentration | 0.2 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CALCA |
| Gene Full Name | Calcitonin |
| Background | This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2014] |
| Function | Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Katacalcin is a potent plasma calcium-lowering peptide. [UniProt] |
| Research Area | Cancer antibody; Cell Biology and Cellular Response antibody; Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 14 kDa |
