ARG23512

anti-Carboxypeptidase A1 antibody

anti-Carboxypeptidase A1 antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Bovine

Overview

Product Description Rabbit Polyclonal antibody recognizes Carboxypeptidase A1.
Rabbit anti Bovine Carboxypeptidase A1 antibody recognizes bovine Carboxypeptidase A1, a 309 amino acid monomeric pancreatic extopeptidase derived by cleavage of the propeptide. Carboxypeptidase A1 belongs to the peptidase M14 family (UniProt: P00370).
Tested Reactivity Hu, Bov
Tested Application ELISA, ICC/IF, IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Carboxypeptidase A1
Antigen Species Bovine
Immunogen Carboxypeptidase A1 from bovine pancreas.
Conjugation Un-conjugated
Alternate Names CPA; Carboxypeptidase A1; EC 3.4.17.1

Application Instructions

Application Suggestion
Tested Application Dilution
ELISAAssay-dependent
ICC/IFAssay-dependent
IHC-P5 µg/ml
WBAssay-dependent
Application Note IHC-P: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purified by ammonium sulfate.
Buffer PBS and 0.01% Sodium azide.
Preservative 0.01% Sodium azide
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1357 Human CPA1

GeneID: 286762 Bovine CPA1

Swiss-port # P00730 Bovine Carboxypeptidase A1

Swiss-port # P15085 Human Carboxypeptidase A1

Gene Symbol CPA1
Gene Full Name carboxypeptidase A1 (pancreatic)
Background This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]
Function Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. [UniProt]
Calculated MW 47 kDa