ARG23512
anti-Carboxypeptidase A1 antibody
anti-Carboxypeptidase A1 antibody for ELISA,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Bovine
Overview
Product Description | Rabbit Polyclonal antibody recognizes Carboxypeptidase A1. Rabbit anti Bovine Carboxypeptidase A1 antibody recognizes bovine Carboxypeptidase A1, a 309 amino acid monomeric pancreatic extopeptidase derived by cleavage of the propeptide. Carboxypeptidase A1 belongs to the peptidase M14 family (UniProt: P00370). |
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Tested Reactivity | Hu, Bov |
Tested Application | ELISA, ICC/IF, IHC-P, WB |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | IgG |
Target Name | Carboxypeptidase A1 |
Antigen Species | Bovine |
Immunogen | Carboxypeptidase A1 from bovine pancreas. |
Conjugation | Un-conjugated |
Alternate Names | CPA; Carboxypeptidase A1; EC 3.4.17.1 |
Application Instructions
Application Suggestion |
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Application Note | IHC-P: This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
Properties
Form | Liquid |
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Purification | Purified by ammonium sulfate. |
Buffer | PBS and 0.01% Sodium azide. |
Preservative | 0.01% Sodium azide |
Concentration | 1 mg/ml |
Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
Database Links | |
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Gene Symbol | CPA1 |
Gene Full Name | carboxypeptidase A1 (pancreatic) |
Background | This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015] |
Function | Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. [UniProt] |
Calculated MW | 47 kDa |