ARG10475
anti-Cardiac Troponin C antibody [7B9]
anti-Cardiac Troponin C antibody [7B9] for Purification,ELISA,Immunoassay,Western blot and Human
Cell Biology and Cellular Response antibody; Signaling Transduction antibody
Overview
| Product Description | Mouse Monoclonal antibody [7B9] recognizes Cardiac Troponin C |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | ELISA, IA, Puri, WB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 7B9 |
| Isotype | IgG1 |
| Target Name | Cardiac Troponin C |
| Antigen Species | Human |
| Immunogen | human cardiac troponin complex |
| Conjugation | Un-conjugated |
| Alternate Names | CMH13; Troponin C, slow skeletal and cardiac muscles; CMD1Z; TNC; TNNC; TN-C |
Application Instructions
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
|---|
Properties
| Form | Liquid |
|---|---|
| Purification | Protein A affinity purified. |
| Buffer | PBS (pH 7.4) and 0.1% Sodium azide |
| Preservative | 0.1% Sodium azide |
| Concentration | 1.0-2.0 mg/ml |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P63316 Human Troponin C, slow skeletal and cardiac muscles |
|---|---|
| Gene Symbol | TNNC1 |
| Gene Full Name | troponin C type 1 (slow) |
| Background | Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008] |
| Function | Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. [UniProt] |
| Research Area | Cell Biology and Cellular Response antibody; Signaling Transduction antibody |
| Calculated MW | 18 kDa |
