ARG44639

anti-Chromogranin A antibody

anti-Chromogranin A antibody for Immunoprecipitation,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody recognizes Chromogranin A
Tested Reactivity Hu
Tested Application IP, WB
Host Mouse
Clonality Monoclonal
Isotype IgG1
Target Name Chromogranin A
Antigen Species Human
Conjugation Un-conjugated
Alternate Names CHGA; Chromogranin A; PHE5; PHES; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; Chromogranin-A; SP-I; Betagranin (N-Terminal Fragment Of Chromogranin A); Pancreastatin; Chromofungin; Vasostatin; Parastatin; Catestatin; CGA; CgA

Application Instructions

Application Suggestion
Tested Application Dilution
IP10 µg/mL
WB1 µg/mL
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Protein A purification
Buffer PBS with 0.09% sodium azide
Preservative 0.09% sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 1113 Human CHGA

Swiss-port # P10645 Human Chromogranin-A

Gene Symbol CHGA
Gene Full Name Chromogranin A
Background The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Function May play a role in the regulation of cardiac function and blood pressure. [UniProt]
Cellular Localization Cytoplasmic vesicle, Secreted. [UniProt]
Calculated MW 51 kDa
PTM Amidation, Cleavage on pair of basic residues, Disulfide bond, Glycoprotein, Oxidation, Phosphoprotein, Proteoglycan, Sulfation. [UniProt]