ARG54577
anti-Chromogranin B antibody
anti-Chromogranin B antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Neuroscience antibody; Signaling Transduction antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Chromogranin B |
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| Tested Reactivity | Hu, Ms, Rat |
| Tested Application | IHC-P, WB |
| Specificity | This antibody recognizes rat, mouse, and human chromogranin B. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Chromogranin B |
| Antigen Species | Human |
| Immunogen | C-terminal 15 amino acids of chromogranin B conjugated to ovalbumin. This sequence is the same in rat, mouse, and human chromogranin B. |
| Conjugation | Un-conjugated |
| Alternate Names | CgB; SCG1; SgI; Secretogranin-1; Secretogranin I; Chromogranin-B |
Application Instructions
| Application Note | This antibody has been used successfully in Western blot assays (1:100 - 1:500 dilution) and in immunohistochemical identification DILUTION INSTRUCTIONS Dilute in PBS or medium which is identical to that used in the assay system. STORAGE AND STABILITY This antibody is stable for at least one (1) year at - 20°C to - 70°C. Store product in appropriate aliquots to avoid multiple freeze - thaw cycles. REFERENCE Thompson ME et al. 1992. Endocrinology 131: 318 - 326. For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures of chromogranin B (1:100 - 1:500) dilution). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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Properties
| Form | Liquid |
|---|---|
| Purification | whole antiserum |
| Buffer | whole antiserum |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
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| Gene Symbol | CHGB |
| Gene Full Name | chromogranin B |
| Background | This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009] |
| Function | Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides. [UniProt] |
| Research Area | Neuroscience antibody; Signaling Transduction antibody |
| Calculated MW | 78 kDa |
| PTM | Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues (By similarity). O-glycosylated. |
