ARG55218
anti-Complexin 1 antibody
anti-Complexin 1 antibody for Western blot and Mouse
Cell Biology>Cell Cycle>Cell Cycle Inhibitors>Cip / Kip> antibody; Signal Transduction>Cytoskeleton / ECM>Cytoskeleton>Microfilaments>Actin etc>Actin Assembly> antibody; Signal Transduction>Signaling Pathway>G Protein Signaling>Heterotrimeric G Proteins>G Proteins> antibody; Epigenetics and Nuclear Signaling>Cell cycle>Cell Cycle Inhibitors>Cip/Kip> antibody; Cancer>Cell cycle>Cell cycle inhibitors>Cip/kip> antibody
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Complexin 1 |
|---|---|
| Tested Reactivity | Ms |
| Predict Reactivity | Bov, Rat |
| Tested Application | WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Complexin 1 |
| Antigen Species | Human |
| Immunogen | KLH-conjugated synthetic peptide corresponding to aa. 51-83 (Center) of Human Complexin 1. |
| Conjugation | Un-conjugated |
| Alternate Names | 921-L; Complexin-2; Synaphin-1; CPX II; CPX-2; CPX2; Complexin II; Hfb1 |
Application Instructions
| Application Suggestion |
|
||||
|---|---|---|---|---|---|
| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| Positive Control | Mouse brain |
Properties
| Form | Liquid |
|---|---|
| Purification | Purification with Protein A and immunogen peptide. |
| Buffer | PBS and 0.09% (W/V) Sodium azide |
| Preservative | 0.09% (W/V) Sodium azide |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links | |
|---|---|
| Gene Symbol | CPLX2 |
| Gene Full Name | complexin 2 |
| Background | Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| Function | Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis (By similarity). [UniProt] |
| Cellular Localization | Cytoplasm, cytosol. Note=Enriched at synaptic-releasing sites in mature neurons. |
| Research Area | Cell Biology>Cell Cycle>Cell Cycle Inhibitors>Cip / Kip> antibody; Signal Transduction>Cytoskeleton / ECM>Cytoskeleton>Microfilaments>Actin etc>Actin Assembly> antibody; Signal Transduction>Signaling Pathway>G Protein Signaling>Heterotrimeric G Proteins>G Proteins> antibody; Epigenetics and Nuclear Signaling>Cell cycle>Cell Cycle Inhibitors>Cip/Kip> antibody; Cancer>Cell cycle>Cell cycle inhibitors>Cip/kip> antibody |
| Calculated MW | 15 kDa |
