ARG55218

anti-Complexin 1 antibody

anti-Complexin 1 antibody for Western blot and Mouse

Cell Biology>Cell Cycle>Cell Cycle Inhibitors>Cip / Kip> antibody; Signal Transduction>Cytoskeleton / ECM>Cytoskeleton>Microfilaments>Actin etc>Actin Assembly> antibody; Signal Transduction>Signaling Pathway>G Protein Signaling>Heterotrimeric G Proteins>G Proteins> antibody; Epigenetics and Nuclear Signaling>Cell cycle>Cell Cycle Inhibitors>Cip/Kip> antibody; Cancer>Cell cycle>Cell cycle inhibitors>Cip/kip> antibody

Overview

Product Description Rabbit Polyclonal antibody recognizes Complexin 1
Tested Reactivity Ms
Predict Reactivity Bov, Rat
Tested Application WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Complexin 1
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide corresponding to aa. 51-83 (Center) of Human Complexin 1.
Conjugation Un-conjugated
Alternate Names 921-L; Complexin-2; Synaphin-1; CPX II; CPX-2; CPX2; Complexin II; Hfb1

Application Instructions

Application Suggestion
Tested Application Dilution
WB1:1000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Mouse brain

Properties

Form Liquid
Purification Purification with Protein A and immunogen peptide.
Buffer PBS and 0.09% (W/V) Sodium azide
Preservative 0.09% (W/V) Sodium azide
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 12890 Mouse CPLX2

Swiss-port # P84086 Mouse Complexin-2

Gene Symbol CPLX2
Gene Full Name complexin 2
Background Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Function Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis (By similarity). [UniProt]
Cellular Localization Cytoplasm, cytosol. Note=Enriched at synaptic-releasing sites in mature neurons.
Research Area Cell Biology>Cell Cycle>Cell Cycle Inhibitors>Cip / Kip> antibody; Signal Transduction>Cytoskeleton / ECM>Cytoskeleton>Microfilaments>Actin etc>Actin Assembly> antibody; Signal Transduction>Signaling Pathway>G Protein Signaling>Heterotrimeric G Proteins>G Proteins> antibody; Epigenetics and Nuclear Signaling>Cell cycle>Cell Cycle Inhibitors>Cip/Kip> antibody; Cancer>Cell cycle>Cell cycle inhibitors>Cip/kip> antibody
Calculated MW 15 kDa