ARG42041

anti-Connexin 36 antibody

anti-Connexin 36 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat

Overview

Product Description Rabbit Polyclonal antibody recognizes Connexin 36
Tested Reactivity Hu, Ms, Rat
Tested Application IHC-P, WB
Host Rabbit
Clonality Polyclonal
Isotype IgG
Target Name Connexin 36
Antigen Species Human
Immunogen KLH-conjugated synthetic peptide between aa. 291-321 of Human Connexin 36.
Conjugation Un-conjugated
Alternate Names GJA9; Cx36; Gap junction delta-2 protein; CX36; Gap junction alpha-9 protein; Connexin-36

Application Instructions

Application Suggestion
Tested Application Dilution
IHC-P1:50 - 1:100
WB1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
Positive Control Human brain
Observed Size ~ 36 kDa

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS and 0.09% (W/V) Sodium azide.
Preservative 0.09% (W/V) Sodium azide.
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 14617 Mouse GJD2

GeneID: 50564 Rat GJD2

GeneID: 57369 Human GJD2

Gene Symbol GJD2
Gene Full Name gap junction protein, delta 2, 36kDa
Background This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012]
Function One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. [UniProt]
Cellular Localization Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. [UniProt]
Calculated MW 36 kDa