ARG56953

anti-Cyclophilin B antibody [k2E2]

anti-Cyclophilin B antibody [k2E2] for Flow cytometry,Western blot and Human

Overview

Product Description Mouse Monoclonal antibody [k2E2] recognizes Cyclophilin B
Tested Reactivity Hu
Tested Application FACS, WB
Host Mouse
Clonality Monoclonal
Clone k2E2
Isotype IgG1, kappa
Target Name Cyclophilin B
Antigen Species Human
Immunogen Recombinant fragment around aa. 26-216 of Human Cyclophilin B.
Conjugation Un-conjugated
Alternate Names HEL-S-39; CYPB; PPIase B; CYP-S1; Cyclophilin B; SCYLP; EC 5.2.1.8; S-cyclophilin; OI9; Rotamase B; Peptidyl-prolyl cis-trans isomerase B

Application Instructions

Application Suggestion
Tested Application Dilution
FACSAssay-dependent
WB1:1000 - 1:2000
Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Properties

Form Liquid
Purification Purification with Protein G.
Buffer PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
Preservative 0.02% Sodium azide
Stabilizer 10% Glycerol
Concentration 1 mg/ml
Storage Instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
Note For laboratory research only, not for drug, diagnostic or other use.

Bioinformation

Database Links

GeneID: 5479 Human PPIB

Swiss-port # P23284 Human Peptidyl-prolyl cis-trans isomerase B

Gene Symbol PPIB
Gene Full Name peptidylprolyl isomerase B (cyclophilin B)
Background The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
Function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [UniProt]
Calculated MW 24 kDa