ARG41517
anti-Cytokeratin 2e antibody
anti-Cytokeratin 2e antibody for Western blot,IHC-Formalin-fixed paraffin-embedded sections and Human
Overview
| Product Description | Rabbit Polyclonal antibody recognizes Cytokeratin 2e |
|---|---|
| Tested Reactivity | Hu |
| Tested Application | IHC-P, WB |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Target Name | Cytokeratin 2e |
| Antigen Species | Human |
| Immunogen | Synthetic peptide of Human Cytokeratin 2e. |
| Conjugation | Un-conjugated |
| Alternate Names | Cytokeratin-2e; K2e; KRTE; Type-II keratin Kb2; Keratin, type II cytoskeletal 2 epidermal; Keratin-2e; CK-2e; Epithelial keratin-2e; KRT2A; Keratin-2 epidermis; KRT2E |
Application Instructions
| Application Suggestion |
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| Application Note | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| Positive Control | A431 | ||||||
| Observed Size | ~ 55 kDa |
Properties
| Form | Liquid |
|---|---|
| Purification | Affinity purified. |
| Buffer | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| Preservative | 0.02% Sodium azide |
| Stabilizer | 50% Glycerol |
| Storage Instruction | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| Note | For laboratory research only, not for drug, diagnostic or other use. |
Bioinformation
| Database Links |
Swiss-port # P35908 Human Keratin, type II cytoskeletal 2 epidermal |
|---|---|
| Gene Symbol | KRT2 |
| Gene Full Name | keratin 2, type II |
| Background | The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008] |
| Function | Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. [UniProt] |
| Calculated MW | 65 kDa |
